Precision Fermentation.
Pilot Scale Validation.
Bench to 1,000 L.
London Bioprocess is a pilot-scale CDMO for precision fermentation and downstream processing. We take yeast, bacterial and fungal processes from bench-scale protocol transfer to a 1,000 L validation batch, to food and cosmetics grade. Our pilot line is moving to Barcelona, with commissioning planned for 2027.
The Scale-Up Problem Is Real
If you’re reading this, you’ve probably already felt it.
cite manufacturing scale-up as their #1 bottleneck
are standard at large CDMOs — your competitors won’t wait
to small validation batches — they are built only for massive, multi-ton industrial runs
Gathering data for FSA/EFSA dossiers adds months to your timeline with partners who lack food-grade standards
Meanwhile, your window of opportunity closes.
End-to-End Fermentation Services
Providing complete precision fermentation services to help startups and established companies turn ideas into scalable, validated products.
Process Development
Bench-scale strain protocol transfer and media screening, then batch and fed-batch process development across yeast, bacterial and fungal strains, planned for scale-up from the start.
Downstream Processing & Analytics
Primary recovery and purification by tubular centrifugation, evaporation, ion exchange and crystallisation. In-house HPLC for sugars, UV-VIS and microscopy, with partner laboratories for other assays.
Scale-Up & Process Validation
A fermentation train from 10 L and 20 L seed vessels through 100 L and 200 L pilot fermenters to a 1,000 L validation fermenter (750 L working volume), with introductions to larger-scale partners for commercial manufacturing.
Pilot Production & Scaling
Pilot batches from 100 L to 1,000 L for regulatory dossiers, market validation and application testing. Drying at pilot scale is through a toll partner, named in your proposal.
Early Scale-Up Validation Bundle
A fixed-scope first programme for seed and Series A teams who need a 100 L proof of concept for investors: bench protocol transfer, then 10 L seed expansion, then a 100 L pilot demonstration. We’re booking programmes for 2027, from commissioning.
Ask about the bundleLab-to-Pilot Fermentation Capacity
Real equipment, verified on site in August and September 2026, now moving to Barcelona for commissioning in 2027.
Seed vessels with pH and DO control. The full equipment list, with photographs taken on site, is available on request.
Downstream & Analytics
Who We Work With
We work best with companies that have a promising fermentation-based product and need proof-of-concept or pilot-scale data.
If you have a molecule that works in the lab and a timeline that matters, we should talk.
Partners & Collaborators
Collaborating with strategic partners, industrial clients and organisations to help build a more sustainable future.
Programmes We Work With
Strategic Partners & Plant Network
From First Call to Dossier-Ready
A clear, staged programme with a fixed scope agreed up front. Steps 3 and 4 make up the Early Scale-Up Validation Bundle.
Discovery Call
We understand your molecule, timeline and regulatory target.
Statement of Work
A fixed scope, price and timeline for your programme, agreed before work starts.
Bench & Seed
Bench-scale strain protocol transfer and media screening, then 10 L and 20 L seed expansion.
Pilot Demonstration & Scale-Up
A 100 L pilot demonstration, then runs of up to 1,000 L, with analytical data for your regulatory dossier.
Dossier-Ready
Downstream processing and delivery of dried product with batch documentation.
Our Experts
London Bioprocess provides end-to-end fermentation and downstream processing across yeast, bacterial and fungal platforms, bridging the valley of death from lab to pilot validation scale.
Frequently Asked Questions
What types of organisms do you work with?
When can we book a run?
Do you work with companies outside the UK/EU?
Who owns the intellectual property generated during a run?
What does a typical engagement cost?
What’s the Early Scale-Up Validation Bundle?
Are you certified?
Ready to Move Your Science Forward?
Let’s talk about your molecule, your timeline, and how we can accelerate your scale-up journey.